Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal d...
Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites
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United States: The American Society for Cell Biology
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English
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United States: The American Society for Cell Biology
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With reconstituted in vitro systems and live cell experiments using optogenetic motor recruitment, we asked how KIF21B motors move with a retrograde bias on mixed polarity microtubule networks. Plus end–out MTs were more dynamic than plus end–in MTs in dendrites. These native MT dynamics contribute to the retrograde bias of cargo movement.
Micro...
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Full title
Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9265162
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9265162
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ISSN
1059-1524
E-ISSN
1939-4586
DOI
10.1091/mbc.E21-10-0480
