A modified fluctuation-test framework characterizes the population dynamics and mutation rate of col...
A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Compelling evidence shows that cancer persister cells represent a major limit to the long-term efficacy of targeted therapies. However, the phenotype and population dynamics of cancer persister cells remain unclear. We developed a quantitative framework to study persisters by combining experimental characterization and mathematical modeling. We fou...
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Full title
A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9279152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9279152
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-022-01105-z
