A randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once dai...
A randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once daily IV busulfan ± clofarabine in allogeneic stem cell transplantation
About this item
Full title
Author / Creator
Andersson, Borje S. , Thall, Peter F. , Ma, Junsheng , Valdez, Benigno C. , Bassett, Roland , Chen, Julianne , Ahmed, Sairah , Alousi, Amin , Bashir, Qaiser , Ciurea, Stefan , Gulbis, Alison , Cool, Rita , Kawedia, Jitesh , Hosing, Chitra , Kebriaei, Partow , Kornblau, Steve , Myers, Alan , Oran, Betul , Rezvani, Katayoun , Shah, Nina , Shpall, Elizabeth , Parmar, Simrit , Popat, Uday R. , Nieto, Yago and Champlin, Richard E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Pretransplant conditioning with Fludarabine (Flu)-Busulfan (Bu) is safe, but clofarabine (Clo) has improved antileukemic activity. Hypothesis: Flu+Clo-Bu (FCB) yields superior progression-free survival (PFS) after allogeneic transplantation. We randomized 250 AML/MDS patients aged 3–70, Karnofsky Score ≥80, with matched donors, to FCB (
n
=...
Alternative Titles
Full title
A randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once daily IV busulfan ± clofarabine in allogeneic stem cell transplantation
Authors, Artists and Contributors
Author / Creator
Thall, Peter F.
Ma, Junsheng
Valdez, Benigno C.
Bassett, Roland
Chen, Julianne
Ahmed, Sairah
Alousi, Amin
Bashir, Qaiser
Ciurea, Stefan
Gulbis, Alison
Cool, Rita
Kawedia, Jitesh
Hosing, Chitra
Kebriaei, Partow
Kornblau, Steve
Myers, Alan
Oran, Betul
Rezvani, Katayoun
Shah, Nina
Shpall, Elizabeth
Parmar, Simrit
Popat, Uday R.
Nieto, Yago
Champlin, Richard E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9352570
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9352570
Other Identifiers
ISSN
0268-3369
E-ISSN
1476-5365
DOI
10.1038/s41409-022-01705-7
