Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL...
Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumours
About this item
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Author / Creator
Huang, Hsi-Chien , Sung, Yun-Chieh , Li, Chung-Pin , Wan, Dehui , Chao, Po-Han , Tseng, Yu-Ting , Liao, Bo-Wen , Cheng, Hui-Teng , Hsu, Fu-Fei , Huang, Chieh-Cheng , Chen, Yi-Ting , Liao, Yu-Hui , Hsieh, Hsin Tzu , Shih, Yu-Chuan , Liu, I-Ju , Wu, Han-Chung , Lu, Tsai-Te , Wang, Jane and Chen, Yunching
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveStromal barriers, such as the abundant desmoplastic stroma that is characteristic of pancreatic ductal adenocarcinoma (PDAC), can block the delivery and decrease the tumour-penetrating ability of therapeutics such as tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), which can selectively induce cancer cell apoptosis. This s...
Alternative Titles
Full title
Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumours
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9380514
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9380514
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2021-325180
