Structural basis of GABA reuptake inhibition
Structural basis of GABA reuptake inhibition
About this item
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
γ-Aminobutyric acid (GABA) transporter 1 (GAT1)
1
regulates neuronal excitation of the central nervous system by clearing the synaptic cleft of the inhibitory neurotransmitter GABA upon its release from synaptic vesicles. Elevating the levels of GABA in the synaptic cleft, by inhibiting GABA reuptake transporters, is an established strategy t...
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Full title
Structural basis of GABA reuptake inhibition
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9394549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9394549
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04814-x
