AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice
AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Gene therapy is a potentially curative medicine for many currently untreatable diseases, and recombinant adeno-associated virus (rAAV) is the most successful gene delivery vehicle for in vivo applications
1
–
3
. However, rAAV-based gene therapy suffers from several limitations, such as constrained DNA cargo size and toxicities caused b...
Alternative Titles
Full title
AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9446716
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9446716
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04533-3
