A microbial supply chain for production of the anti-cancer drug vinblastine
A microbial supply chain for production of the anti-cancer drug vinblastine
About this item
Full title
Author / Creator
Zhang, Jie , Hansen, Lea G. , Gudich, Olga , Viehrig, Konrad , Lassen, Lærke M. M. , Schrübbers, Lars , Adhikari, Khem B. , Rubaszka, Paulina , Carrasquer-Alvarez, Elena , Chen, Ling , D’Ambrosio, Vasil , Lehka, Beata , Haidar, Ahmad K. , Nallapareddy, Saranya , Giannakou, Konstantina , Laloux, Marcos , Arsovska, Dushica , Jørgensen, Marcus A. K. , Chan, Leanne Jade G. , Kristensen, Mette , Christensen, Hanne B. , Sudarsan, Suresh , Stander, Emily A. , Baidoo, Edward , Petzold, Christopher J. , Wulff, Tune , O’Connor, Sarah E. , Courdavault, Vincent , Jensen, Michael K. , Keasling, Jay D. and Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine
1
. As MIAs are difficult to chemically synthesize, the world’s supply chain for vinblastine relies on low-yielding extraction and purifica...
Alternative Titles
Full title
A microbial supply chain for production of the anti-cancer drug vinblastine
Authors, Artists and Contributors
Author / Creator
Hansen, Lea G.
Gudich, Olga
Viehrig, Konrad
Lassen, Lærke M. M.
Schrübbers, Lars
Adhikari, Khem B.
Rubaszka, Paulina
Carrasquer-Alvarez, Elena
Chen, Ling
D’Ambrosio, Vasil
Lehka, Beata
Haidar, Ahmad K.
Nallapareddy, Saranya
Giannakou, Konstantina
Laloux, Marcos
Arsovska, Dushica
Jørgensen, Marcus A. K.
Chan, Leanne Jade G.
Kristensen, Mette
Christensen, Hanne B.
Sudarsan, Suresh
Stander, Emily A.
Baidoo, Edward
Petzold, Christopher J.
Wulff, Tune
O’Connor, Sarah E.
Courdavault, Vincent
Jensen, Michael K.
Keasling, Jay D.
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9452304
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9452304
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-05157-3
