A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein
A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Protein tertiary structure mimetics are valuable tools to target large protein–protein interaction interfaces. Here, we demonstrate a strategy for designing dimeric helix-hairpin motifs from a previously reported three-helix-bundle miniprotein that targets the receptor-binding domain (RBD) of severe acute respiratory syndrome-coronavirus-2 (SARS-Co...
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A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9512702
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9512702
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ISSN
1552-4450,1552-4469
E-ISSN
1552-4469
DOI
10.1038/s41589-022-01060-0