Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aort...
Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aortic phenotype in young mice
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Publisher
United States: Elsevier Ltd
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Language
English
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Publisher
United States: Elsevier Ltd
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Contents
Mechanical homeostasis emerges following normal development of the arterial wall and requires thereafter a slow balanced degradation and deposition of extracellular matrix constituents within an unchanging mechanical state. Recent findings suggest that homeostasis is compromised in arterial aging, which contributes to the structural stiffening that...
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Full title
Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aortic phenotype in young mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9585962
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9585962
Other Identifiers
ISSN
0021-9290,1873-2380
E-ISSN
1873-2380
DOI
10.1016/j.jbiomech.2022.111179
