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Antisense Oligonucleotides for the Study and Treatment of ALS

Antisense Oligonucleotides for the Study and Treatment of ALS

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9587169

Antisense Oligonucleotides for the Study and Treatment of ALS

About this item

Full title

Antisense Oligonucleotides for the Study and Treatment of ALS

Publisher

Cham: Springer International Publishing

Journal title

Neurotherapeutics, 2022-07, Vol.19 (4), p.1145-1158

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by motor neuron loss. ALS is now associated with mutations in numerous genes, many of which cause disease in part through toxic gain-of-function mechanisms. Antisense oligonucleotides (ASOs) are small sequences of DNA that can reduce expression of a target gene a...

Alternative Titles

Full title

Antisense Oligonucleotides for the Study and Treatment of ALS

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9587169

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9587169

Other Identifiers

ISSN

1933-7213,1878-7479

E-ISSN

1878-7479

DOI

10.1007/s13311-022-01247-2

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