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Third-generation EGFR and ALK inhibitors: mechanisms of resistance and management

Third-generation EGFR and ALK inhibitors: mechanisms of resistance and management

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9621058

Third-generation EGFR and ALK inhibitors: mechanisms of resistance and management

About this item

Full title

Third-generation EGFR and ALK inhibitors: mechanisms of resistance and management

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Clinical oncology, 2022-08, Vol.19 (8), p.499-514

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The discoveries of
EGFR
mutations and
ALK
rearrangements as actionable oncogenic drivers in non-small-cell lung cancer (NSCLC) has propelled a biomarker-directed treatment paradigm for patients with advanced-stage disease. Numerous EGFR and ALK tyrosine kinase inhibitors (TKIs) with demonstrated efficacy in patients with
EGFR
-mut...

Alternative Titles

Full title

Third-generation EGFR and ALK inhibitors: mechanisms of resistance and management

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9621058

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9621058

Other Identifiers

ISSN

1759-4774,1759-4782

E-ISSN

1759-4782

DOI

10.1038/s41571-022-00639-9

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