Tuberous Sclerosis Complex 1 Deficiency in Macrophages Promotes Unclassical Inflammatory Response to...
Tuberous Sclerosis Complex 1 Deficiency in Macrophages Promotes Unclassical Inflammatory Response to Lipopolysaccharide In Vitro and Dextran Sodium Sulfate-Induced Colitis in Mice
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Author / Creator
Xu, Huawen , Zhao, Yang , Zhao, Qingjie , Shi, Mingpu , Zhang, Zhaoqi , Ding, Wenjun and Zhao, Yong
Publisher
JKL International
Journal title
Language
English
Formats
Publication information
Publisher
JKL International
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Scope and Contents
Contents
Human tuberous sclerosis (TSC) is mainly caused by genetic mutations of tuberous TSC1or TSC2. Recent studies found that TSC1 deficiency promoted classical M1 macrophage polarization. However, whether TSC1 regulates other inflammatory cytokine expression in lipopolysaccharidem (LPS)-stimulated macrophages is unknown. Herein, we studied the cytokine...
Alternative Titles
Full title
Tuberous Sclerosis Complex 1 Deficiency in Macrophages Promotes Unclassical Inflammatory Response to Lipopolysaccharide In Vitro and Dextran Sodium Sulfate-Induced Colitis in Mice
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9662278
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9662278
Other Identifiers
ISSN
2152-5250
E-ISSN
2152-5250
DOI
10.14336/AD.2022.0408
