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Combined Treatment of Dichloroacetic Acid and Pyruvate Increased Neuronal Survival after Seizure

Combined Treatment of Dichloroacetic Acid and Pyruvate Increased Neuronal Survival after Seizure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9698956

Combined Treatment of Dichloroacetic Acid and Pyruvate Increased Neuronal Survival after Seizure

About this item

Full title

Combined Treatment of Dichloroacetic Acid and Pyruvate Increased Neuronal Survival after Seizure

Publisher

Switzerland: MDPI AG

Journal title

Nutrients, 2022-11, Vol.14 (22), p.4804

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

During seizure activity, glucose and Adenosine triphosphate (ATP) levels are significantly decreased in the brain, which is a contributing factor to seizure-induced neuronal death. Dichloroacetic acid (DCA) has been shown to prevent cell death. DCA is also known to be involved in adenosine triphosphate (ATP) production by activating pyruvate dehydr...

Alternative Titles

Full title

Combined Treatment of Dichloroacetic Acid and Pyruvate Increased Neuronal Survival after Seizure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9698956

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9698956

Other Identifiers

ISSN

2072-6643

E-ISSN

2072-6643

DOI

10.3390/nu14224804

How to access this item