A shared disease-associated oligodendrocyte signature among multiple CNS pathologies
A shared disease-associated oligodendrocyte signature among multiple CNS pathologies
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Alzheimer’s disease (AD) is a complex neurodegenerative disease, perturbing neuronal and non-neuronal cell populations. In this study, using single-cell transcriptomics, we mapped all non-immune, non-neuronal cell populations in wild-type and AD model (5xFAD) mouse brains. We identified an oligodendrocyte state that increased in association with br...
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A shared disease-associated oligodendrocyte signature among multiple CNS pathologies
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9724210
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9724210
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-022-01104-7