Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer's dise...
Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer's disease
About this item
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Author / Creator
Shu, Shu , Xu, Si-Yi , Ye, Lei , Liu, Yi , Cao, Xiang , Jia, Jun-Qiu , Bian, Hui-Jie , Liu, Ying , Zhu, Xiao-Lei and Xu, Yun
Publisher
England: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
England: Nature Publishing Group
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Scope and Contents
Contents
Alzheimer's disease (AD) is the most common neurodegenerative disease and has an insidious onset. Exploring the characteristics and mechanism of the early symptoms of AD plays a critical role in the early diagnosis and intervention of AD. Here we found that depressive-like behavior and short-term spatial memory dysfunction appeared in APPswe/PS1dE9...
Alternative Titles
Full title
Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9750960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9750960
Other Identifiers
ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-022-01435-w
