CSF tau microtubule-binding region identifies pathological changes in primary tauopathies
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies
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Full title
Author / Creator
Horie, Kanta , Barthélemy, Nicolas R. , Spina, Salvatore , VandeVrede, Lawren , He, Yingxin , Paterson, Ross W. , Wright, Brenton A. , Day, Gregory S. , Davis, Albert A. , Karch, Celeste M. , Seeley, William W. , Perrin, Richard J. , Koppisetti, Rama K. , Shaikh, Faris , Lago, Argentina Lario , Heuer, Hilary W. , Ghoshal, Nupur , Gabelle, Audrey , Miller, Bruce L. , Boxer, Adam L. , Bateman, Randall J. and Sato, Chihiro
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Despite recent advances in fluid biomarker research in Alzheimer’s disease (AD), there are no fluid biomarkers or imaging tracers with utility for diagnosis and/or theragnosis available for other tauopathies. Using immunoprecipitation and mass spectrometry, we show that 4 repeat (4R) isoform-specific tau species from microtubule-binding region (MTB...
Alternative Titles
Full title
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies
Authors, Artists and Contributors
Author / Creator
Barthélemy, Nicolas R.
Spina, Salvatore
VandeVrede, Lawren
He, Yingxin
Paterson, Ross W.
Wright, Brenton A.
Day, Gregory S.
Davis, Albert A.
Karch, Celeste M.
Seeley, William W.
Perrin, Richard J.
Koppisetti, Rama K.
Shaikh, Faris
Lago, Argentina Lario
Heuer, Hilary W.
Ghoshal, Nupur
Gabelle, Audrey
Miller, Bruce L.
Boxer, Adam L.
Bateman, Randall J.
Sato, Chihiro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9800273
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9800273
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-022-02075-9
