Recurrent repeat expansions in human cancer genomes
Recurrent repeat expansions in human cancer genomes
About this item
Full title
Author / Creator
Erwin, Graham S. , Gürsoy, Gamze , Al-Abri, Rashid , Suriyaprakash, Ashwini , Dolzhenko, Egor , Zhu, Kevin , Hoerner, Christian R. , White, Shannon M. , Ramirez, Lucia , Vadlakonda, Ananya , Vadlakonda, Alekhya , von Kraut, Konor , Park, Julia , Brannon, Charlotte M. , Sumano, Daniel A. , Kirtikar, Raushun A. , Erwin, Alicia A. , Metzner, Thomas J. , Yuen, Ryan K. C. , Fan, Alice C. , Leppert, John T. , Eberle, Michael A. , Gerstein, Mark and Snyder, Michael P.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Expansion of a single repetitive DNA sequence, termed a tandem repeat (TR), is known to cause more than 50 diseases
1
,
2
. However, repeat expansions are often not explored beyond neurological and neurodegenerative disorders. In some cancers, mutations accumulate in short tracts of TRs, a phenomenon termed microsatellite instability; h...
Alternative Titles
Full title
Recurrent repeat expansions in human cancer genomes
Authors, Artists and Contributors
Author / Creator
Gürsoy, Gamze
Al-Abri, Rashid
Suriyaprakash, Ashwini
Dolzhenko, Egor
Zhu, Kevin
Hoerner, Christian R.
White, Shannon M.
Ramirez, Lucia
Vadlakonda, Ananya
Vadlakonda, Alekhya
von Kraut, Konor
Park, Julia
Brannon, Charlotte M.
Sumano, Daniel A.
Kirtikar, Raushun A.
Erwin, Alicia A.
Metzner, Thomas J.
Yuen, Ryan K. C.
Fan, Alice C.
Leppert, John T.
Eberle, Michael A.
Gerstein, Mark
Snyder, Michael P.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9812771
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9812771
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-05515-1
