Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer
Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer
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Full title
Author / Creator
ARASENS Trial Investigators , Smith, Matthew R , Hussain, Maha , Saad, Fred , Fizazi, Karim , Sternberg, Cora N , Crawford, E. David , Kopyltsov, Evgeny , Park, Chandler H , Alekseev, Boris , Montesa-Pino, Álvaro , Ye, Dingwei , Parnis, Francis , Cruz, Felipe , Tammela, Teuvo L.J , Suzuki, Hiroyoshi , Utriainen, Tapio , Fu, Cheng , Uemura, Motohide , Méndez-Vidal, María J , Maughan, Benjamin L , Joensuu, Heikki , Thiele, Silke , Li, Rui , Kuss, Iris and Tombal, Bertrand
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
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Publication information
Publisher
United States: Massachusetts Medical Society
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More information
Scope and Contents
Contents
Standard therapy for metastatic, hormone-sensitive prostate cancer is androgen-deprivation therapy, usually with docetaxel. A large, multinational, phase 3 trial assessed the addition of the androgen-receptor blocker darolutamide to standard therapy. At 4 years, survival was higher with darolutamide than with placebo (62.7% vs. 50.4%), with no majo...
Alternative Titles
Full title
Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer
Authors, Artists and Contributors
Author / Creator
Smith, Matthew R
Hussain, Maha
Saad, Fred
Fizazi, Karim
Sternberg, Cora N
Crawford, E. David
Kopyltsov, Evgeny
Park, Chandler H
Alekseev, Boris
Montesa-Pino, Álvaro
Ye, Dingwei
Parnis, Francis
Cruz, Felipe
Tammela, Teuvo L.J
Suzuki, Hiroyoshi
Utriainen, Tapio
Fu, Cheng
Uemura, Motohide
Méndez-Vidal, María J
Maughan, Benjamin L
Joensuu, Heikki
Thiele, Silke
Li, Rui
Kuss, Iris
Tombal, Bertrand
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9844551
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9844551
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2119115
