γδ T cells are effectors of immunotherapy in cancers with HLA class I defects
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects
About this item
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Author / Creator
de Vries, Natasja L. , van de Haar, Joris , Veninga, Vivien , Chalabi, Myriam , Ijsselsteijn, Marieke E. , van der Ploeg, Manon , van den Bulk, Jitske , Ruano, Dina , van den Berg, Jose G. , Haanen, John B. , Zeverijn, Laurien J. , Geurts, Birgit S. , de Wit, Gijs F. , Battaglia, Thomas W. , Gelderblom, Hans , Verheul, Henk M. W. , Schumacher, Ton N. , Wessels, Lodewyk F. A. , Koning, Frits , de Miranda, Noel F. C. C. and Voest, Emile E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
DNA mismatch repair-deficient (MMR-d) cancers present an abundance of neoantigens that is thought to explain their exceptional responsiveness to immune checkpoint blockade (ICB)
1
,
2
. Here, in contrast to other cancer types
3
–
5
, we observed that 20 out of 21 (95%) MMR-d cancers with genomic inactivation of β2-microglobu...
Alternative Titles
Full title
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects
Authors, Artists and Contributors
Author / Creator
van de Haar, Joris
Veninga, Vivien
Chalabi, Myriam
Ijsselsteijn, Marieke E.
van der Ploeg, Manon
van den Bulk, Jitske
Ruano, Dina
van den Berg, Jose G.
Haanen, John B.
Zeverijn, Laurien J.
Geurts, Birgit S.
de Wit, Gijs F.
Battaglia, Thomas W.
Gelderblom, Hans
Verheul, Henk M. W.
Schumacher, Ton N.
Wessels, Lodewyk F. A.
Koning, Frits
de Miranda, Noel F. C. C.
Voest, Emile E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9876799
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9876799
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-022-05593-1