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γδ T cells are effectors of immunotherapy in cancers with HLA class I defects

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9876799

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects

About this item

Full title

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-01, Vol.613 (7945), p.743-750

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

DNA mismatch repair-deficient (MMR-d) cancers present an abundance of neoantigens that is thought to explain their exceptional responsiveness to immune checkpoint blockade (ICB)
1
,
2
. Here, in contrast to other cancer types
3

5
, we observed that 20 out of 21 (95%) MMR-d cancers with genomic inactivation of β2-microglobu...

Alternative Titles

Full title

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9876799

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9876799

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-022-05593-1

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