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Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C

Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9908297

Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C

About this item

Full title

Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2023-01, Vol.388 (1), p.44-54

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

In heavily pretreated patients with mutant KRAS G12C colorectal cancer, adagrasib induced a response in 19% as single agent and in 46% in combination with cetuximab, an epidermal growth factor receptor antibody.

Alternative Titles

Full title

Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9908297

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9908297

Other Identifiers

ISSN

0028-4793,1533-4406

E-ISSN

1533-4406

DOI

10.1056/NEJMoa2212419

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