A randomized phase I/II safety and immunogenicity study of the Montanide-adjuvanted SARS-CoV-2 spike...
A randomized phase I/II safety and immunogenicity study of the Montanide-adjuvanted SARS-CoV-2 spike protein-RBD-Fc vaccine, AKS-452
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Full title
Author / Creator
Feitsma, Eline A , Janssen, Yester F , Boersma, Hendrikus H , van Sleen, Yannick , van Baarle, Debbie , Alleva, David G , Lancaster, Thomas M , Sathiyaseelan, Thillainaygam , Murikipudi, Sylaja , Delpero, Andrea R , Scully, Melanie M , Ragupathy, Ramya , Kotha, Sravya , Haworth, Jeffrey R , Shah, Nishit J , Rao, Vidhya , Nagre, Shashikant , Ronca, Shannon E , Green, Freedom M , Aminetzah, Ari , Sollie, Frans , Kruijff, Schelto , Brom, Maarten , van Dam, Gooitzen M and Zion, Todd C
Publisher
Netherlands: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Netherlands: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
AbstractBackgroundPrevious interim data from a phase I study of AKS-452, a subunit vaccine comprising an Fc fusion of the respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein receptor binding domain (SP/RBD) emulsified in the water-in-oil adjuvant, Montanide™ ISA 720, suggested a good safety and immunogenicity profile in healthy adults. Th...
Alternative Titles
Full title
A randomized phase I/II safety and immunogenicity study of the Montanide-adjuvanted SARS-CoV-2 spike protein-RBD-Fc vaccine, AKS-452
Authors, Artists and Contributors
Author / Creator
Janssen, Yester F
Boersma, Hendrikus H
van Sleen, Yannick
van Baarle, Debbie
Alleva, David G
Lancaster, Thomas M
Sathiyaseelan, Thillainaygam
Murikipudi, Sylaja
Delpero, Andrea R
Scully, Melanie M
Ragupathy, Ramya
Kotha, Sravya
Haworth, Jeffrey R
Shah, Nishit J
Rao, Vidhya
Nagre, Shashikant
Ronca, Shannon E
Green, Freedom M
Aminetzah, Ari
Sollie, Frans
Kruijff, Schelto
Brom, Maarten
van Dam, Gooitzen M
Zion, Todd C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9946892
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9946892
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2023.02.057
