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A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial c...

A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9947015

A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer

About this item

Full title

A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer Immunology, Immunotherapy, 2023-03, Vol.72 (3), p.759-767

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

PD1 inhibition is effective in patients with metastatic urothelial cancer (mUC), yet a large fraction of patients does not respond. In this study, we aimed to identify a blood-based immune marker associated with non-response to facilitate patient selection for anti-PD1. To this end, we quantified 18 immune cell populations using multiplex flow cyto...

Alternative Titles

Full title

A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9947015

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9947015

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851

DOI

10.1007/s00262-022-03250-0

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