Second-line therapy in pancreatic ductal adenocarcinoma (PDAC) patients with germline BRCA1-2 pathog...
Second-line therapy in pancreatic ductal adenocarcinoma (PDAC) patients with germline BRCA1-2 pathogenic variants (gBRCA1-2pv)
About this item
Full title
Author / Creator
Orsi, Giulia , Cavaliere, Alessandro , Tortora, Giampaolo , Lonardi, Sara , Macchini, Marina , Di Marco, Mariacristina , Giordano, Guido , Vasile, Enrico , Scartozzi, Mario , Bozzarelli, Silvia , Noventa, Silvia , Rodriquenz, Maria Grazia , Militello, Anna Maria , Rapposelli, Ilario Giovanni , Garajova, Ingrid , De Lorenzo, Stefania , Merelli, Barbara , Bittoni, Alessandro , Salvatore, Lisa , Procaccio, Letizia , Paratore, Chiara , Spallanzani, Andrea , Peretti, Umberto , Niger, Monica , Giommoni, Elisa , Bernardini, Ilaria , Tamburini, Emiliano , Bernardino, Katia , Forti, Laura , Valente, Maria Maddalena , Cascinu, Stefano , Milella, Michele and Reni, Michele
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background
Pancreatic ductal adenocarcinoma (PDAC) harbouring germline BRCA1-2 pathogenic variants (gBRCA1-2pv) is a distinct nosological entity. Information on second-line therapy (2LT) outcome in this setting is lacking.
Methods
Data of gBRCA1-2pv metastatic PDAC patients treated with chemotherapy were collected. A primary analysis of 2L...
Alternative Titles
Full title
Second-line therapy in pancreatic ductal adenocarcinoma (PDAC) patients with germline BRCA1-2 pathogenic variants (gBRCA1-2pv)
Authors, Artists and Contributors
Author / Creator
Cavaliere, Alessandro
Tortora, Giampaolo
Lonardi, Sara
Macchini, Marina
Di Marco, Mariacristina
Giordano, Guido
Vasile, Enrico
Scartozzi, Mario
Bozzarelli, Silvia
Noventa, Silvia
Rodriquenz, Maria Grazia
Militello, Anna Maria
Rapposelli, Ilario Giovanni
Garajova, Ingrid
De Lorenzo, Stefania
Merelli, Barbara
Bittoni, Alessandro
Salvatore, Lisa
Procaccio, Letizia
Paratore, Chiara
Spallanzani, Andrea
Peretti, Umberto
Niger, Monica
Giommoni, Elisa
Bernardini, Ilaria
Tamburini, Emiliano
Bernardino, Katia
Forti, Laura
Valente, Maria Maddalena
Cascinu, Stefano
Milella, Michele
Reni, Michele
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9977912
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9977912
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-022-02086-w
