The use of fluorophore-assisted carbohydrate electrophoresis (FACE) in the regulatory assessment of...
The use of fluorophore-assisted carbohydrate electrophoresis (FACE) in the regulatory assessment of the N-linked sugars of therapeutic glycoproteins
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Glycosylation is the major post-translational modification of proteins and plays a major role in the activity, pharmacokinetics and immunologic of proteins. Therapeutic glycoproteins produced by recombinant mammalian cell lines therefore require analysis of their sugar moieties. We have analysed the sugars attached to recombinant gonadotropins, cyt...
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The use of fluorophore-assisted carbohydrate electrophoresis (FACE) in the regulatory assessment of the N-linked sugars of therapeutic glycoproteins
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TN_cdi_rmit_collectionsjats_10_3316_informit_557803295389630
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_rmit_collectionsjats_10_3316_informit_557803295389630
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1441-0834
