Fatal interactions and reactions with colchicine: beware CYP3A4 inhibitors
Fatal interactions and reactions with colchicine: beware CYP3A4 inhibitors
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Full title
Fatal interactions and reactions with colchicine: beware CYP3A4 inhibitors
Journal title
Australian adverse drug reactions bulletin, 2008-10, Vol.27 (5), p.18
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Contents
Since colchicine is metabolised mainly by CYP3A4, prescribers should be aware that drugs that inhibit this enzyme may increase blood colchicine concentrations and therefore increase the potential for colchicine toxicity. The CYP3A4 inhibitor, clarithromycin, was used concomitantly in 4 cases of severe colchicine toxicity reported to the TGA, 3 of w...
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Full title
Fatal interactions and reactions with colchicine: beware CYP3A4 inhibitors
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TN_cdi_rmit_collectionsjats_10_3316_informit_561585788555044
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_rmit_collectionsjats_10_3316_informit_561585788555044
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ISSN
0812-3837
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