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C.difficile intoxicates neurons and pericytes to drive neurogenic inflammation

C.difficile intoxicates neurons and pericytes to drive neurogenic inflammation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_springer_journals_10_1038_s41586_023_06607_2

C.difficile intoxicates neurons and pericytes to drive neurogenic inflammation

About this item

Full title

C.difficile intoxicates neurons and pericytes to drive neurogenic inflammation

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-10, Vol.622 (7983), p.611-618

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Clostridioides difficile
infection (CDI) is a major cause of healthcare-associated gastrointestinal infections
1
,
2
. The exaggerated colonic inflammation caused by
C.

difficile
toxins such as toxin B (TcdB) damages tissues and promotes
C.

difficile
colonization
3

6
, but how TcdB causes inf...

Alternative Titles

Full title

C.difficile intoxicates neurons and pericytes to drive neurogenic inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_springer_journals_10_1038_s41586_023_06607_2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_springer_journals_10_1038_s41586_023_06607_2

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06607-2

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