Structure of dual receptor binding to botulinum neurotoxin B
Structure of dual receptor binding to botulinum neurotoxin B
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Botulinum neurotoxins are highly toxic, and bind two receptors to achieve their high affinity and specificity for neurons. Here we present the first structure of a botulinum neurotoxin bound to both its receptors. We determine the 2.3-Å structure of a ternary complex of botulinum neurotoxin type B bound to both its protein receptor synaptotagmin II...
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Full title
Structure of dual receptor binding to botulinum neurotoxin B
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TN_cdi_swepub_primary_oai_DiVA_org_su_94056
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_su_94056
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms3058
