TREM2 regulates microglial cell activation in response to demyelination in vivo
TREM2 regulates microglial cell activation in response to demyelination in vivo
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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More information
Scope and Contents
Contents
Microglia are phagocytic cells that survey the brain and perform neuroprotective functions in response to tissue damage, but their activating receptors are largely unknown. Triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial immunoreceptor whose loss-of-function mutations in humans cause presenile dementia, while genetic varian...
Alternative Titles
Full title
TREM2 regulates microglial cell activation in response to demyelination in vivo
Authors, Artists and Contributors
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_umu_101377
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_101377
Other Identifiers
ISSN
0001-6322,1432-0533
E-ISSN
1432-0533
DOI
10.1007/s00401-015-1388-1
