DNA interstrand cross-link repair requires replication-fork convergence
DNA interstrand cross-link repair requires replication-fork convergence
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
New biochemical analyses in
Xenopus
cell-free extracts show that two replication forks must converge on a DNA interstrand cross-link (ICL) to permit translesion synthesis and repair.
DNA interstrand cross-links (ICLs) prevent strand separation during DNA replication and transcription and therefore are extremely cytotoxic. In metazoans, a m...
Alternative Titles
Full title
DNA interstrand cross-link repair requires replication-fork convergence
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_umu_230641
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_230641
Other Identifiers
ISSN
1545-9993,1545-9985
E-ISSN
1545-9985
DOI
10.1038/nsmb.2956
