Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases
Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases
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Publisher
Danvers, MA: Elsevier Inc
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Language
English
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Publisher
Danvers, MA: Elsevier Inc
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Contents
Proteinase-activated receptor-2 (PAR2) is a seven transmembrane spanning, G-protein-coupled receptor, present on the membrane of many cell types including keratinocytes. In skin, PAR2 is suggested to play a regulatory role during inflammation, epidermal barrier function, and pruritus. PAR2 is activated by trypsin-like proteases by a unique mechanis...
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Full title
Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases
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TN_cdi_swepub_primary_oai_DiVA_org_umu_7000
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_7000
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ISSN
0022-202X,1523-1747
E-ISSN
1523-1747
DOI
10.1038/sj.jid.5700965