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Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_7000

Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

About this item

Full title

Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

Publisher

Danvers, MA: Elsevier Inc

Journal title

Journal of investigative dermatology, 2008-01, Vol.128 (1), p.18-25

Language

English

Formats

Publication information

Publisher

Danvers, MA: Elsevier Inc

More information

Scope and Contents

Contents

Proteinase-activated receptor-2 (PAR2) is a seven transmembrane spanning, G-protein-coupled receptor, present on the membrane of many cell types including keratinocytes. In skin, PAR2 is suggested to play a regulatory role during inflammation, epidermal barrier function, and pruritus. PAR2 is activated by trypsin-like proteases by a unique mechanis...

Alternative Titles

Full title

Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_umu_7000

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_umu_7000

Other Identifiers

ISSN

0022-202X,1523-1747

E-ISSN

1523-1747

DOI

10.1038/sj.jid.5700965