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Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using...

Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_22173

Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using Rat Model

About this item

Full title

Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using Rat Model

Publisher

New York, NY: Springer

Journal title

Pharmaceutical research, 2006-08, Vol.23 (8), p.1675-1686

Language

English

Formats

Publication information

Publisher

New York, NY: Springer

More information

Scope and Contents

Contents

To study the correlation of intestinal absorption for drugs with various absorption routes between human and rat, and to explore the underlying molecular mechanisms for the similarity in drug intestinal absorption and the differences in oral bioavailability between human and rat.
The intestinal permeabilities of 14 drugs and three drug-like comp...

Alternative Titles

Full title

Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human Using Rat Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_22173

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_22173

Other Identifiers

ISSN

0724-8741,1573-904X

E-ISSN

1573-904X

DOI

10.1007/s11095-006-9041-2