Quantification of [18F]DPA-714 Binding in the Human Brain: Initial Studies in Healthy Controls and A...
Quantification of [18F]DPA-714 Binding in the Human Brain: Initial Studies in Healthy Controls and Alzheimer'S Disease Patients
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Author / Creator
Golla, Sandeep SV , Boellaard, Ronald , Oikonen, Vesa , Hoffmann, Anja , van Berckel, Bart NM , Windhorst, Albert D , Virta, Jere , Haaparanta-Solin, Merja , Luoto, Pauliina , Savisto, Nina , Solin, Olof , Valencia, Ray , Thiele, Andrea , Eriksson, Jonas , Schuit, Robert C , Lammertsma, Adriaan A and Rinne, Juha O
Publisher
London, England: SAGE Publications
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Language
English
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Publisher
London, England: SAGE Publications
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Contents
Fluorine-18 labelled N,N-diethyl-2-(2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-α]pyrimidine-3-yl)acetamide ([18F] DPA-714) binds to the 18-kDa translocator protein (TSPO) with high affinity. The aim of this initial methodological study was to develop a plasma input tracer kinetic model for quantification of [18F]DPA-714 binding in health...
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Full title
Quantification of [18F]DPA-714 Binding in the Human Brain: Initial Studies in Healthy Controls and Alzheimer'S Disease Patients
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_256612
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_256612
Other Identifiers
ISSN
0271-678X,1559-7016
E-ISSN
1559-7016
DOI
10.1038/jcbfm.2014.261
