5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma
5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma
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Publisher
Germany: BioMed Central Ltd
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Language
English
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Publisher
Germany: BioMed Central Ltd
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Contents
Primary hyperparathyroidism is characterized by enlarged parathyroid glands due to an adenoma (80-85 %) or multiglandular disease (~15 %) causing hypersecretion of parathyroid hormone (PTH) and generally hypercalcemia. Parathyroid cancer is rare (<1-5 %). The epigenetic mark 5-hydroxymethylcytosine (5hmC) is reduced in various cancers, and this may...
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Full title
5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma
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TN_cdi_swepub_primary_oai_DiVA_org_uu_282795
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_282795
Other Identifiers
ISSN
1868-7075,1868-7083
E-ISSN
1868-7083,1868-7075
DOI
10.1186/s13148-016-0197-2
