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Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft mo...

Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft mo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_297897

Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model

About this item

Full title

Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-04, Vol.6 (1), p.24968-24968, Article 24968

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The transforming growth factor-β (TGF-β) family is known to play critical roles in cancer progression. While the dual role of TGF-β is well described, the function of bone morphogenetic proteins (BMPs) is unclear. In this study, we established the involvement of Smad6, a BMP-specific inhibitory Smad, in breast cancer cell invasion. We show that sta...

Alternative Titles

Full title

Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_297897

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_297897

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep24968

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