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Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_369397

Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

About this item

Full title

Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-11, Vol.8 (1), p.16318-13, Article 16318

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The proteasomal system is responsible for the turnover of damaged proteins. Because of its important functions in oncogenesis, inhibiting the proteasomal system is a promising therapeutic approach for cancer treatment. Bortezomib (BTZ) is the first proteasome inhibitor approved by FDA for clinical applications. However neuropathic side effects are...

Alternative Titles

Full title

Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_369397

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_369397

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-34507-3

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