Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and ph...
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
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Author / Creator
International COPD Genetics Consortium , SpiroMeta Consortium , Understanding Society Scientific Group , Sakornsakolpat, Phuwanat , Prokopenko, Dmitry , Lamontagne, Maxime , Reeve, Nicola F. , Guyatt, Anna L. , Jackson, Victoria E. , Shrine, Nick , Qiao, Dandi , Bartz, Traci M. , Kim, Deog Kyeom , Lee, Mi Kyeong , Latourelle, Jeanne C. , Li, Xingnan , Morrow, Jarrett D. , Obeidat, Ma’en , Wyss, Annah B. , Bakke, Per , Barr, R. Graham , Beaty, Terri H. , Belinsky, Steven A. , Brusselle, Guy G. , Crapo, James D. , de Jong, Kim , DeMeo, Dawn L. , Fingerlin, Tasha E. , Gharib, Sina A. , Gulsvik, Amund , Hall, Ian P. , Hokanson, John E. , Kim, Woo Jin , Lomas, David A. , London, Stephanie J. , Meyers, Deborah A. , O’Connor, George T. , Rennard, Stephen I. , Schwartz, David A. , Sliwinski, Pawel , Sparrow, David , Strachan, David P. , Tal-Singer, Ruth , Tesfaigzi, Yohannes , Vestbo, Jørgen , Vonk, Judith M. , Yim, Jae-Joon , Zhou, Xiaobo , Bossé, Yohan , Manichaikul, Ani , Lahousse, Lies , Silverman, Edwin K. , Boezen, H. Marike , Wain, Louise V. , Tobin, Martin D. , Hobbs, Brian D. and Cho, Michael H.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed a genome-wide association study in 35,735 cases and 222,076 controls from the UK Biobank and additional studies from the International COPD Genetics Consortium. We ident...
Alternative Titles
Full title
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
Authors, Artists and Contributors
Author / Creator
SpiroMeta Consortium
Understanding Society Scientific Group
Sakornsakolpat, Phuwanat
Prokopenko, Dmitry
Lamontagne, Maxime
Reeve, Nicola F.
Guyatt, Anna L.
Jackson, Victoria E.
Shrine, Nick
Qiao, Dandi
Bartz, Traci M.
Kim, Deog Kyeom
Lee, Mi Kyeong
Latourelle, Jeanne C.
Li, Xingnan
Morrow, Jarrett D.
Obeidat, Ma’en
Wyss, Annah B.
Bakke, Per
Barr, R. Graham
Beaty, Terri H.
Belinsky, Steven A.
Brusselle, Guy G.
Crapo, James D.
de Jong, Kim
DeMeo, Dawn L.
Fingerlin, Tasha E.
Gharib, Sina A.
Gulsvik, Amund
Hall, Ian P.
Hokanson, John E.
Kim, Woo Jin
Lomas, David A.
London, Stephanie J.
Meyers, Deborah A.
O’Connor, George T.
Rennard, Stephen I.
Schwartz, David A.
Sliwinski, Pawel
Sparrow, David
Strachan, David P.
Tal-Singer, Ruth
Tesfaigzi, Yohannes
Vestbo, Jørgen
Vonk, Judith M.
Yim, Jae-Joon
Zhou, Xiaobo
Bossé, Yohan
Manichaikul, Ani
Lahousse, Lies
Silverman, Edwin K.
Boezen, H. Marike
Wain, Louise V.
Tobin, Martin D.
Hobbs, Brian D.
Cho, Michael H.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_379346
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_379346
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-018-0342-2
