Analytical and preparative separation of phosphorothioated oligonucleotides: columns and ion-pair re...
Analytical and preparative separation of phosphorothioated oligonucleotides: columns and ion-pair reagents
About this item
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Oligonucleotide drugs represent an emerging area in the pharmaceutical industry. Solid-phase synthesis generates many structurally closely related impurities, making efficient separation systems for purification and analysis a key challenge during pharmaceutical drug development. To increase the fundamental understanding of the important preparativ...
Alternative Titles
Full title
Analytical and preparative separation of phosphorothioated oligonucleotides: columns and ion-pair reagents
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_408220
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_408220
Other Identifiers
ISSN
1618-2642,1618-2650
E-ISSN
1618-2650
DOI
10.1007/s00216-019-02236-9