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Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with St...

Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with St...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_444398

Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with Standard Assessments

About this item

Full title

Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with Standard Assessments

Publisher

Cham: Springer International Publishing

Journal title

The AAPS journal, 2021-05, Vol.23 (3), p.63-63, Article 63

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Longitudinal pharmacometric models offer many advantages in the analysis of clinical trial data, but potentially inflated type I error and biased drug effect estimates, as a consequence of model misspecifications and multiple testing, are main drawbacks. In this work, we used real data to compare these aspects for a standard approach (STD) and a ne...

Alternative Titles

Full title

Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with Standard Assessments

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_444398

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_444398

Other Identifiers

ISSN

1550-7416

E-ISSN

1550-7416

DOI

10.1208/s12248-021-00596-8

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