Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with St...
Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with Standard Assessments
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Cham: Springer International Publishing
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English
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Cham: Springer International Publishing
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Longitudinal pharmacometric models offer many advantages in the analysis of clinical trial data, but potentially inflated type I error and biased drug effect estimates, as a consequence of model misspecifications and multiple testing, are main drawbacks. In this work, we used real data to compare these aspects for a standard approach (STD) and a ne...
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Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with Standard Assessments
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TN_cdi_swepub_primary_oai_DiVA_org_uu_444398
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_444398
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ISSN
1550-7416
E-ISSN
1550-7416
DOI
10.1208/s12248-021-00596-8