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The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s...

The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_454735

The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease

About this item

Full title

The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2021-07, Vol.142 (1), p.17-39

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Reminiscent of the human prion diseases, there is considerable clinical and pathological variability in Alzheimer’s disease, the most common human neurodegenerative condition. As in prion disorders, protein misfolding and aggregation is a hallmark feature of Alzheimer’s disease, where the initiating event is thought to be the self-assembly of Aβ pe...

Alternative Titles

Full title

The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_454735

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_454735

Other Identifiers

ISSN

0001-6322,1432-0533

E-ISSN

1432-0533

DOI

10.1007/s00401-020-02201-2

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