The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s...
The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Reminiscent of the human prion diseases, there is considerable clinical and pathological variability in Alzheimer’s disease, the most common human neurodegenerative condition. As in prion disorders, protein misfolding and aggregation is a hallmark feature of Alzheimer’s disease, where the initiating event is thought to be the self-assembly of Aβ pe...
Alternative Titles
Full title
The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease
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Author / Creator
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Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_454735
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_454735
Other Identifiers
ISSN
0001-6322,1432-0533
E-ISSN
1432-0533
DOI
10.1007/s00401-020-02201-2