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Trends in kinase drug discovery: targets, indications and inhibitor design

Trends in kinase drug discovery: targets, indications and inhibitor design

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_469669

Trends in kinase drug discovery: targets, indications and inhibitor design

About this item

Full title

Trends in kinase drug discovery: targets, indications and inhibitor design

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Drug discovery, 2021-11, Vol.20 (11), p.839-861

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The FDA approval of imatinib in 2001 was a breakthrough in molecularly targeted cancer therapy and heralded the emergence of kinase inhibitors as a key drug class in the oncology area and beyond. Twenty years on, this article analyses the landscape of approved and investigational therapies that target kinases and trends within it, including the mos...

Alternative Titles

Full title

Trends in kinase drug discovery: targets, indications and inhibitor design

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_469669

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_469669

Other Identifiers

ISSN

1474-1776,1474-1784

E-ISSN

1474-1784

DOI

10.1038/s41573-021-00252-y

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