Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer developme...
Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development
About this item
Full title
Author / Creator
Xu, Qin , Wang, Chao , Zhou, Jia-Xin , Xu, Zhi-Mei , Gao, Juan , Sui, Pengfei , Walsh, Colum P. , Ji, Hongbin and Xu, Guo-Liang
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Oncogenic imbalance of DNA methylation is well recognized in cancer development. The ten-eleven translocation (TET) family of dioxygenases, which facilitates DNA demethylation, is frequently dysregulated in cancers. How such dysregulation contributes to tumorigenesis remains poorly understood, especially in solid tumors which present infrequent mut...
Alternative Titles
Full title
Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_470674
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_470674
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2107599119
