Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
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Author / Creator
Genomics England Research Consortium , Pleguezuelos-Manzano, Cayetano , Puschhof, Jens , Rosendahl Huber, Axel , van Hoeck, Arne , Wood, Henry M. , Nomburg, Jason , Gurjao, Carino , Manders, Freek , Dalmasso, Guillaume , Stege, Paul B. , Paganelli, Fernanda L. , Geurts, Maarten H. , Beumer, Joep , Mizutani, Tomohiro , Miao, Yi , van der Linden, Reinier , van der Elst, Stefan , Garcia, K. Christopher , Top, Janetta , Willems, Rob J. L. , Giannakis, Marios , Bonnet, Richard , Quirke, Phil , Meyerson, Matthew , Cuppen, Edwin , van Boxtel, Ruben and Clevers, Hans
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Various species of the intestinal microbiota have been associated with the development of colorectal cancer
1
,
2
, but it has not been demonstrated that bacteria have a direct role in the occurrence of oncogenic mutations.
Escherichia coli
can carry the pathogenicity island
pks
, which encodes a set of enzymes that synthesi...
Alternative Titles
Full title
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
Authors, Artists and Contributors
Author / Creator
Pleguezuelos-Manzano, Cayetano
Puschhof, Jens
Rosendahl Huber, Axel
van Hoeck, Arne
Wood, Henry M.
Nomburg, Jason
Gurjao, Carino
Manders, Freek
Dalmasso, Guillaume
Stege, Paul B.
Paganelli, Fernanda L.
Geurts, Maarten H.
Beumer, Joep
Mizutani, Tomohiro
Miao, Yi
van der Linden, Reinier
van der Elst, Stefan
Garcia, K. Christopher
Top, Janetta
Willems, Rob J. L.
Giannakis, Marios
Bonnet, Richard
Quirke, Phil
Meyerson, Matthew
Cuppen, Edwin
van Boxtel, Ruben
Clevers, Hans
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_511044
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_511044
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2080-8
