Identification of constrained sequence elements across 239 primate genomes
Identification of constrained sequence elements across 239 primate genomes
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Author / Creator
Kuderna, Lukas F. K. , Ulirsch, Jacob C. , Rashid, Sabrina , Ameen, Mohamed , Sundaram, Laksshman , Hickey, Glenn , Cox, Anthony J. , Gao, Hong , Kumar, Arvind , Aguet, Francois , Christmas, Matthew J. , Clawson, Hiram , Haeussler, Maximilian , Janiak, Mareike C. , Kuhlwilm, Martin , Orkin, Joseph D. , Bataillon, Thomas , Manu, Shivakumara , Valenzuela, Alejandro , Bergman, Juraj , Rouselle, Marjolaine , Silva, Felipe Ennes , Agueda, Lidia , Blanc, Julie , Gut, Marta , de Vries, Dorien , Goodhead, Ian , Harris, R. Alan , Raveendran, Muthuswamy , Jensen, Axel , Chuma, Idriss S. , Horvath, Julie E. , Hvilsom, Christina , Juan, David , Frandsen, Peter , Schraiber, Joshua G. , de Melo, Fabiano R. , Bertuol, Fabrício , Byrne, Hazel , Sampaio, Iracilda , Farias, Izeni , Valsecchi, João , Messias, Malu , da Silva, Maria N. F. , Trivedi, Mihir , Rossi, Rogerio , Hrbek, Tomas , Andriaholinirina, Nicole , Rabarivola, Clément J. , Zaramody, Alphonse , Jolly, Clifford J. , Phillips-Conroy, Jane , Wilkerson, Gregory , Abee, Christian , Simmons, Joe H. , Fernandez-Duque, Eduardo , Kanthaswamy, Sree , Shiferaw, Fekadu , Wu, Dongdong , Zhou, Long , Shao, Yong , Zhang, Guojie , Keyyu, Julius D. , Knauf, Sascha , Le, Minh D. , Lizano, Esther , Merker, Stefan , Navarro, Arcadi , Nadler, Tilo , Khor, Chiea Chuen , Lee, Jessica , Tan, Patrick , Lim, Weng Khong , Kitchener, Andrew C. , Zinner, Dietmar , Gut, Ivo , Melin, Amanda D. , Guschanski, Katerina , Schierup, Mikkel Heide , Beck, Robin M. D. , Karakikes, Ioannis , Wang, Kevin C. , Umapathy, Govindhaswamy , Roos, Christian , Boubli, Jean P. , Siepel, Adam , Kundaje, Anshul , Paten, Benedict , Lindblad-Toh, Kerstin , Rogers, Jeffrey , Marques Bonet, Tomas and Farh, Kyle Kai-How
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Noncoding DNA is central to our understanding of human gene regulation and complex diseases
1
,
2
, and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome
3
–
9
. Identifying the genomic elements that have become constrained specifically i...
Alternative Titles
Full title
Identification of constrained sequence elements across 239 primate genomes
Authors, Artists and Contributors
Author / Creator
Ulirsch, Jacob C.
Rashid, Sabrina
Ameen, Mohamed
Sundaram, Laksshman
Hickey, Glenn
Cox, Anthony J.
Gao, Hong
Kumar, Arvind
Aguet, Francois
Christmas, Matthew J.
Clawson, Hiram
Haeussler, Maximilian
Janiak, Mareike C.
Kuhlwilm, Martin
Orkin, Joseph D.
Bataillon, Thomas
Manu, Shivakumara
Valenzuela, Alejandro
Bergman, Juraj
Rouselle, Marjolaine
Silva, Felipe Ennes
Agueda, Lidia
Blanc, Julie
Gut, Marta
de Vries, Dorien
Goodhead, Ian
Harris, R. Alan
Raveendran, Muthuswamy
Jensen, Axel
Chuma, Idriss S.
Horvath, Julie E.
Hvilsom, Christina
Juan, David
Frandsen, Peter
Schraiber, Joshua G.
de Melo, Fabiano R.
Bertuol, Fabrício
Byrne, Hazel
Sampaio, Iracilda
Farias, Izeni
Valsecchi, João
Messias, Malu
da Silva, Maria N. F.
Trivedi, Mihir
Rossi, Rogerio
Hrbek, Tomas
Andriaholinirina, Nicole
Rabarivola, Clément J.
Zaramody, Alphonse
Jolly, Clifford J.
Phillips-Conroy, Jane
Wilkerson, Gregory
Abee, Christian
Simmons, Joe H.
Fernandez-Duque, Eduardo
Kanthaswamy, Sree
Shiferaw, Fekadu
Wu, Dongdong
Zhou, Long
Shao, Yong
Zhang, Guojie
Keyyu, Julius D.
Knauf, Sascha
Le, Minh D.
Lizano, Esther
Merker, Stefan
Navarro, Arcadi
Nadler, Tilo
Khor, Chiea Chuen
Lee, Jessica
Tan, Patrick
Lim, Weng Khong
Kitchener, Andrew C.
Zinner, Dietmar
Gut, Ivo
Melin, Amanda D.
Guschanski, Katerina
Schierup, Mikkel Heide
Beck, Robin M. D.
Karakikes, Ioannis
Wang, Kevin C.
Umapathy, Govindhaswamy
Roos, Christian
Boubli, Jean P.
Siepel, Adam
Kundaje, Anshul
Paten, Benedict
Lindblad-Toh, Kerstin
Rogers, Jeffrey
Marques Bonet, Tomas
Farh, Kyle Kai-How
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_DiVA_org_uu_520342
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_520342
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06798-8