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Identification of constrained sequence elements across 239 primate genomes

Identification of constrained sequence elements across 239 primate genomes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_520342

Identification of constrained sequence elements across 239 primate genomes

About this item

Full title

Identification of constrained sequence elements across 239 primate genomes

Author / Creator

Kuderna, Lukas F. K. , Ulirsch, Jacob C. , Rashid, Sabrina , Ameen, Mohamed , Sundaram, Laksshman , Hickey, Glenn , Cox, Anthony J. , Gao, Hong , Kumar, Arvind , Aguet, Francois , Christmas, Matthew J. , Clawson, Hiram , Haeussler, Maximilian , Janiak, Mareike C. , Kuhlwilm, Martin , Orkin, Joseph D. , Bataillon, Thomas , Manu, Shivakumara , Valenzuela, Alejandro , Bergman, Juraj , Rouselle, Marjolaine , Silva, Felipe Ennes , Agueda, Lidia , Blanc, Julie , Gut, Marta , de Vries, Dorien , Goodhead, Ian , Harris, R. Alan , Raveendran, Muthuswamy , Jensen, Axel , Chuma, Idriss S. , Horvath, Julie E. , Hvilsom, Christina , Juan, David , Frandsen, Peter , Schraiber, Joshua G. , de Melo, Fabiano R. , Bertuol, Fabrício , Byrne, Hazel , Sampaio, Iracilda , Farias, Izeni , Valsecchi, João , Messias, Malu , da Silva, Maria N. F. , Trivedi, Mihir , Rossi, Rogerio , Hrbek, Tomas , Andriaholinirina, Nicole , Rabarivola, Clément J. , Zaramody, Alphonse , Jolly, Clifford J. , Phillips-Conroy, Jane , Wilkerson, Gregory , Abee, Christian , Simmons, Joe H. , Fernandez-Duque, Eduardo , Kanthaswamy, Sree , Shiferaw, Fekadu , Wu, Dongdong , Zhou, Long , Shao, Yong , Zhang, Guojie , Keyyu, Julius D. , Knauf, Sascha , Le, Minh D. , Lizano, Esther , Merker, Stefan , Navarro, Arcadi , Nadler, Tilo , Khor, Chiea Chuen , Lee, Jessica , Tan, Patrick , Lim, Weng Khong , Kitchener, Andrew C. , Zinner, Dietmar , Gut, Ivo , Melin, Amanda D. , Guschanski, Katerina , Schierup, Mikkel Heide , Beck, Robin M. D. , Karakikes, Ioannis , Wang, Kevin C. , Umapathy, Govindhaswamy , Roos, Christian , Boubli, Jean P. , Siepel, Adam , Kundaje, Anshul , Paten, Benedict , Lindblad-Toh, Kerstin , Rogers, Jeffrey , Marques Bonet, Tomas and Farh, Kyle Kai-How

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2024-01, Vol.625 (7996), p.735-742

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Noncoding DNA is central to our understanding of human gene regulation and complex diseases
1
,
2
, and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome
3

9
. Identifying the genomic elements that have become constrained specifically i...

Alternative Titles

Full title

Identification of constrained sequence elements across 239 primate genomes

Authors, Artists and Contributors

Author / Creator

Kuderna, Lukas F. K.
Ulirsch, Jacob C.
Rashid, Sabrina
Ameen, Mohamed
Sundaram, Laksshman
Hickey, Glenn
Cox, Anthony J.
Gao, Hong
Kumar, Arvind
Aguet, Francois
Christmas, Matthew J.
Clawson, Hiram
Haeussler, Maximilian
Janiak, Mareike C.
Kuhlwilm, Martin
Orkin, Joseph D.
Bataillon, Thomas
Manu, Shivakumara
Valenzuela, Alejandro
Bergman, Juraj
Rouselle, Marjolaine
Silva, Felipe Ennes
Agueda, Lidia
Blanc, Julie
Gut, Marta
de Vries, Dorien
Goodhead, Ian
Harris, R. Alan
Raveendran, Muthuswamy
Jensen, Axel
Chuma, Idriss S.
Horvath, Julie E.
Hvilsom, Christina
Juan, David
Frandsen, Peter
Schraiber, Joshua G.
de Melo, Fabiano R.
Bertuol, Fabrício
Byrne, Hazel
Sampaio, Iracilda
Farias, Izeni
Valsecchi, João
Messias, Malu
da Silva, Maria N. F.
Trivedi, Mihir
Rossi, Rogerio
Hrbek, Tomas
Andriaholinirina, Nicole
Rabarivola, Clément J.
Zaramody, Alphonse
Jolly, Clifford J.
Phillips-Conroy, Jane
Wilkerson, Gregory
Abee, Christian
Simmons, Joe H.
Fernandez-Duque, Eduardo
Kanthaswamy, Sree
Shiferaw, Fekadu
Wu, Dongdong
Zhou, Long
Shao, Yong
Zhang, Guojie
Keyyu, Julius D.
Knauf, Sascha
Le, Minh D.
Lizano, Esther
Merker, Stefan
Navarro, Arcadi
Nadler, Tilo
Khor, Chiea Chuen
Lee, Jessica
Tan, Patrick
Lim, Weng Khong
Kitchener, Andrew C.
Zinner, Dietmar
Gut, Ivo
Melin, Amanda D.
Guschanski, Katerina
Schierup, Mikkel Heide
Beck, Robin M. D.
Karakikes, Ioannis
Wang, Kevin C.
Umapathy, Govindhaswamy
Roos, Christian
Boubli, Jean P.
Siepel, Adam
Kundaje, Anshul
Paten, Benedict
Lindblad-Toh, Kerstin
Rogers, Jeffrey
Marques Bonet, Tomas
Farh, Kyle Kai-How

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_DiVA_org_uu_520342

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_520342

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06798-8

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