Structural diversity of G protein-coupled receptors and significance for drug discovery
Structural diversity of G protein-coupled receptors and significance for drug discovery
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The elucidation of the primary structure of the first identified G-protein-coupled receptor (GPCR) rhodopsin 25 years ago was a key step in the development of the concept of a GPCR superfamily. Now, data from our recent mining of the human genome suggests that humans have at least 799 full-length GPCRs, making them the largest superfa...
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Structural diversity of G protein-coupled receptors and significance for drug discovery
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TN_cdi_swepub_primary_oai_DiVA_org_uu_99132
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_DiVA_org_uu_99132
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1474-1776,1474-1784
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1474-1784,1474-1776
DOI
10.1038/nrd2518
