Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomi...
Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
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Author / Creator
Dodel, Richard, Prof , Rominger, Axel, MD , Bartenstein, Peter, MD , Barkhof, Frederik, MD , Blennow, Kaj, PhD , Förster, Stefan, MD , Winter, Yaroslav, MD , Bach, Jan-Philipp, MD , Popp, Julius, MD , Alferink, Judith, MD , Wiltfang, Jens, MD , Buerger, Katharina, MD , Otto, Markus, MD , Antuono, Piero, MD , Jacoby, Michael, MD , Richter, Ralph, MD , Stevens, James, MD , Melamed, Isaac, MD , Goldstein, Jerome, MD , Haag, Stefan, MD , Wietek, Stefan, PhD , Farlow, Martin, MD and Jessen, Frank, MD
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Three small trials suggest that intravenous immunoglobulin can affect biomarkers and symptoms of mild-to-moderate Alzheimer's disease. We tested the safety, effective dose, and infusion interval of intravenous immunoglobulin in such patients. Methods We did a multicentre, placebo-controlled phase 2 trial at seven sites in the USA...
Alternative Titles
Full title
Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
Authors, Artists and Contributors
Author / Creator
Rominger, Axel, MD
Bartenstein, Peter, MD
Barkhof, Frederik, MD
Blennow, Kaj, PhD
Förster, Stefan, MD
Winter, Yaroslav, MD
Bach, Jan-Philipp, MD
Popp, Julius, MD
Alferink, Judith, MD
Wiltfang, Jens, MD
Buerger, Katharina, MD
Otto, Markus, MD
Antuono, Piero, MD
Jacoby, Michael, MD
Richter, Ralph, MD
Stevens, James, MD
Melamed, Isaac, MD
Goldstein, Jerome, MD
Haag, Stefan, MD
Wietek, Stefan, PhD
Farlow, Martin, MD
Jessen, Frank, MD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_184650
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_184650
Other Identifiers
ISSN
1474-4422,1474-4465
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(13)70014-0