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Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patient...

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patient...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_214948

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients

About this item

Full title

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2015-05, Vol.125 (5), p.1979-1986

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Quantification of disease-associated proteins in the cerebrospinal fluid (CSF) has been critical for the study and treatment of several neurodegenerative disorders; however, mutant huntingtin protein (mHTT), the cause of Huntington's disease (HD), is at very low levels in CSF and, to our knowledge, has never been measured previously.
We develope...

Alternative Titles

Full title

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_gup_ub_gu_se_214948

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_214948

Other Identifiers

ISSN

0021-9738,1558-8238

E-ISSN

1558-8238

DOI

10.1172/JCI80743

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