A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in huma...
A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Amyloid β-protein oligomers play a key role in Alzheimer's disease (AD), but well-validated assays that routinely detect them in cerebrospinal fluid (CSF) are just emerging. We sought to confirm and extend a recent study using the Singulex Erenna platform that reported increased mean CSF oligomer levels in AD.
We tested four antibody pairs and c...
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Full title
A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid
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TN_cdi_swepub_primary_oai_gup_ub_gu_se_214949
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_214949
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ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-015-0100-y
