Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a mul...
Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG
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Author / Creator
Institute of Neuroscience and Physiology , Sahlgrenska akademin , Göteborgs universitet , Gothenburg University , Sahlgrenska Academy , Institutionen för neurovetenskap och fysiologi , Carter, Stephen F , Schöll, Michael , Almkvist, Ove , Wall, Anders , Engler, Henry , Långström, Bengt and Nordberg, Agneta
Publisher
United States
Journal title
Language
English
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Publisher
United States
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Contents
Astrocytes colocalize with fibrillar amyloid-β (Aβ) plaques in postmortem Alzheimer disease (AD) brain tissue. It is therefore of great interest to develop a PET tracer for visualizing astrocytes in vivo, enabling the study of the regional distribution of both astrocytes and fibrillar Aβ. A multitracer PET investigation was conducted for patients w...
Alternative Titles
Full title
Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG
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Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_250574
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_250574
Other Identifiers
ISSN
0161-5505,1535-5667
E-ISSN
1535-5667
DOI
10.2967/jnumed.110.087031
