Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological...
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
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Full title
Author / Creator
Rasmussen, Jay , Mahler, Jasmin , Beschorner, Natalie , Kaeser, Stephan A. , Häsler, Lisa M. , Baumann, Frank , Nyström, Sofie , Portelius, Erik , Blennow, Kaj , Lashley, Tammaryn , Fox, Nick C. , Sepulveda-Falla, Diego , Glatzel, Markus , Oblak, Adrian L. , Ghetti, Bernardino , Nilsson, K. Peter R. , Hammarström, Per , Staufenbiel, Matthias , Walker, Lary C. and Jucker, Mathias
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The molecular architecture of amyloids formed in vivo can be interrogated using luminescent conjugated oligothiophenes (LCOs), a unique class of amyloid dyes. When bound to amyloid, LCOs yield fluorescence emission spectra that reflect the 3D structure of the protein aggregates. Given that synthetic amyloid-β peptide (Aβ) has been shown to adopt di...
Alternative Titles
Full title
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Mahler, Jasmin
Beschorner, Natalie
Kaeser, Stephan A.
Häsler, Lisa M.
Baumann, Frank
Nyström, Sofie
Portelius, Erik
Blennow, Kaj
Lashley, Tammaryn
Fox, Nick C.
Sepulveda-Falla, Diego
Glatzel, Markus
Oblak, Adrian L.
Ghetti, Bernardino
Nilsson, K. Peter R.
Hammarström, Per
Staufenbiel, Matthias
Walker, Lary C.
Jucker, Mathias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_260544
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_260544
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1713215114
