Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes
Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes
About this item
Full title
Author / Creator
Oduori, Okechi S , Murao, Naoya , Shimomura, Kenju , Takahashi, Harumi , Zhang, Quan , Dou, Haiqiang , Sakai, Shihomi , Minami, Kohtaro , Chanclon, Belen , Guida, Claudia , Kothegala, Lakshmi , Tolö, Johan , Maejima, Yuko , Yokoi, Norihide , Minami, Yasuhiro , Miki, Takashi , Rorsman, Patrik and Seino, Susumu
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
By restoring glucose-regulated insulin secretion, glucagon-like peptide-1-based (GLP-1-based) therapies are becoming increasingly important in diabetes care. Normally, the incretins GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) jointly maintain normal blood glucose levels by stimulation of insulin secretion in pancreatic β cells. How...
Alternative Titles
Full title
Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_gup_ub_gu_se_301054
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_gup_ub_gu_se_301054
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI140046
